Tetraphenylethylene-embedded pillar[5]arene-based orthogonal self-assembly for efficient photocatalysis in water

• Zhihang Bai,
• Krishnasamy Velmurugan,
• Xueqi Tian,
• Minzan Zuo,
• Kaiya Wang and
• Xiao-Yu Hu

Beilstein J. Org. Chem. 2022, 18, 429–437, doi:10.3762/bjoc.18.45

• intramolecular phenyl-ring rotations and functioned as an ideal donor. After the loading of eosin Y (EsY) as acceptor on the surface of the assembly of m-TPEWP5 and G, the worm-like nanostructures changed into nanorods, which facilitates a Förster resonance energy transfer (FRET) from the m-TPEWP5 and G

• photosynthesis and exhibited a high catalytic efficiency for the photocatalytic dehalogenation reaction of various bromoketone derivatives with good yields in short reaction time in water. Keywords: aggregation-induced emission; Förster resonance energy transfer; host–guest interaction; photocatalysis

Synthesis of 10-O-aryl-substituted berberine derivatives by Chan–Evans–Lam coupling and investigation of their DNA-binding properties

• Peter Jonas Wickhorst,
• Mathilda Blachnik,
• Denisa Lagumdzija and
• Heiko Ihmels

Beilstein J. Org. Chem. 2021, 17, 991–1000, doi:10.3762/bjoc.17.81

• monitoring of the temperature-dependent Förster resonance energy transfer (FRET) between the dyes [46]. The particular oligonucleotide sequences were chosen because they are known to be involved in biologically relevant processes, namely in the transcription regulation of myc (FmycT) [47][48], kit (FkitT

Changed reactivity of secondary hydroxy groups in C8-modified adenosine – lessons learned from silylation

• Jennifer Frommer and
• Sabine Müller

Beilstein J. Org. Chem. 2020, 16, 2854–2861, doi:10.3762/bjoc.16.234

• nucleic acids via Förster Resonance Energy Transfer (FRET) [20]. More recently, we started an effort to develop an efficient strategy for the preparation of a linker-modified adenosine building block, which in a future project is to be used for post synthetic conjugation of reporters or functional

Synthesis and investigation of quadruplex-DNA-binding, 9-O-substituted berberine derivatives

• Jonas Becher,
• Daria V. Berdnikova,
• Heiko Ihmels and
• Christopher Stremmel

Beilstein J. Org. Chem. 2020, 16, 2795–2806, doi:10.3762/bjoc.16.230

• experiments. For that purpose, the DNA melting temperature Tm of the dye-labeled oligonucleotides F21T and Fa2T (for sequence see caption of Figure 2) was monitored by fluorescence spectroscopy, as the thermally induced unfolding of the quadruplex disrupts the Förster resonance energy transfer (FRET) between

Encrypting messages with artificial bacterial receptors

• Pragati Kishore Prasad,
• Naama Lahav-Mankovski,
• Leila Motiei and
• David Margulies

Beilstein J. Org. Chem. 2020, 16, 2749–2756, doi:10.3762/bjoc.16.225

• receptors is described. We show that the binding of DNA-based artificial receptors to E. coli expressing His-tagged outer membrane protein C (His-OmpC) induces a Förster resonance energy transfer (FRET) between the dyes, which results in the generation of a unique fluorescence fingerprint. Because the

Optical detection of di- and triphosphate anions with mixed monolayer-protected gold nanoparticles containing zinc(II)–dipicolylamine complexes

• Lena Reinke,
• Julia Bartl,
• Marcus Koch and
• Stefan Kubik

Beilstein J. Org. Chem. 2020, 16, 2687–2700, doi:10.3762/bjoc.16.219

• quenched in the absence of the analyte by Förster resonance energy transfer (FRET). In the latter case, the analyte binding either causes the chromophore to dissociate from the nanoparticle, if it is bound noncovalently (indicator displacement), or to move away from the metal surface as a consequence of a

Heterogeneous photocatalysis in flow chemical reactors

• Christopher G. Thomson,
• Ai-Lan Lee and
• Filipe Vilela

Beilstein J. Org. Chem. 2020, 16, 1495–1549, doi:10.3762/bjoc.16.125

Aggregation-induced emission effect on turn-off fluorescent switching of a photochromic diarylethene

• Luna Kono,
• Yuma Nakagawa,
• Ayako Fujimoto,
• Ryo Nishimura,
• Yohei Hattori,
• Toshiki Mutai,
• Nobuhiro Yasuda,
• Kenichi Koizumi,
• Satoshi Yokojima,
• Shinichiro Nakamura and
• Kingo Uchida

Beilstein J. Org. Chem. 2019, 15, 2204–2212, doi:10.3762/bjoc.15.217

• intermolecular Förster Resonance Energy Transfer (FRET) process between the fluorescent units and the photochromic moieties in their closed form within the aggregated state [29]. The crystal did not show any vapochromism, while a dramatic fluorescent color change from green to pink was observed when chloroform

Rational design of boron-dipyrromethene (BODIPY) reporter dyes for cucurbit[7]uril

• Mohammad A. Alnajjar,
• Jürgen Bartelmeß,
• Robert Hein,
• Pichandi Ashokkumar,
• Mohamed Nilam,
• Werner M. Nau,
• Knut Rurack and
• Andreas Hennig

Beilstein J. Org. Chem. 2018, 14, 1961–1971, doi:10.3762/bjoc.14.171

• the macrocycle would be desirable. One possibility is the utilization of monofunctionalized CBs with outer cavity-attached fluorescent dyes [22][24]. This principally allows for the modular construction of various Förster resonance energy transfer (FRET) pairs as demonstrated with a Cy3-attached CB7

Fluorescent nucleobase analogues for base–base FRET in nucleic acids: synthesis, photophysics and applications

• Mattias Bood,
• Sangamesh Sarangamath,
• Moa S. Wranne,
• Morten Grøtli and
• L. Marcus Wilhelmsson

Beilstein J. Org. Chem. 2018, 14, 114–129, doi:10.3762/bjoc.14.7

• , SE-412 96 Gothenburg, Sweden 10.3762/bjoc.14.7 Abstract Förster resonance energy transfer (FRET) between a donor nucleobase analogue and an acceptor nucleobase analogue, base–base FRET, works as a spectroscopic ruler and protractor. With their firm stacking and ability to replace the natural nucleic

• that complements NMR and X-ray, normally at lower resolution, is Förster resonance energy transfer (FRET) [3][4]. FRET and especially single-molecule FRET (as an effect of a low number of biomolecules under study) has the advantage of enabling structure and dynamics investigations in living cells [3][5

Muraymycin nucleoside-peptide antibiotics: uridine-derived natural products as lead structures for the development of novel antibacterial agents

• Daniel Wiegmann,
• Stefan Koppermann,
• Marius Wirth,
• Giuliana Niro,
• Kristin Leyerer and
• Christian Ducho

Beilstein J. Org. Chem. 2016, 12, 769–795, doi:10.3762/bjoc.12.77

• are three different assays available that provide such inhibition data: i) a fluorescence-based and ii) a radioactivity-based assay as well as iii) a relatively new Förster resonance energy transfer (FRET)-based method. The fluorescence-based assay was developed by Bugg et al. [79][80] and uses a

A comparative study of the interactions of cationic hetarenes with quadruplex-DNA forming oligonucleotide sequences of the insulin-linked polymorphic region (ILPR)

• Darinka Dzubiel,
• Heiko Ihmels,
• Mohamed M. A. Mahmoud and
• Laura Thomas

Beilstein J. Org. Chem. 2014, 10, 2963–2974, doi:10.3762/bjoc.10.314

• fluorimetric monitoring of the temperature-dependent Förster resonance energy transfer (FRET) between the dyes [29]. In sodium cacodylate buffer (10 mM Na+, 10 mM K+, 90 mM Li+) the melting curve of the DNA has a weak transition at 50 °C and a more pronounced one at Tm = 71.0 °C (Figure 4). The results of the

Synthesis and optical properties of pyrrolidinyl peptide nucleic acid carrying a clicked Nile red label

• Nattawut Yotapan,
• Chayan Charoenpakdee,
• Pawinee Wathanathavorn,
• Boonsong Ditmangklo,
• Hans-Achim Wagenknecht and
• Tirayut Vilaivan

Beilstein J. Org. Chem. 2014, 10, 2166–2174, doi:10.3762/bjoc.10.224

• biomolecular interactions [1][2][3]. Traditionally, the biological macromolecules are labeled with two or more dyes which can interact in a conformation/distant-dependent manner via Förster resonance energy transfer (FRET) [4][5][6]. Alternatively, the FRET pairs can be replaced by an environmentally sensitive

Supramolecular FRET photocyclodimerization of anthracenecarboxylate with naphthalene-capped γ-cyclodextrin

• Qian Wang,
• Cheng Yang,
• Gaku Fukuhara,
• Tadashi Mori,
• Yu Liu and
• Yoshihisa Inoue

Beilstein J. Org. Chem. 2011, 7, 290–297, doi:10.3762/bjoc.7.38

• .7.38 Abstract γ-Cyclodextrin (CD) derivatives with a naphthalene moiety anchored to one or two of the glucose units of the CD were synthesized in order to investigate the effects of flexible and rigid capping upon complexation, as well as Förster resonance energy transfer (FRET) and photochirogenic

• Förster resonance energy transfer (FRET) sensitization. Results and Discussion Naphthalene-capped γ-CD 6 was synthesized by the reaction of 6A,6C-ditosyl-γ-CD [23] with disodium 2,6-naphthalenedicarboxylate in DMSO. An attempt to synthesize the regioisomeric 6A,6D-(2,6-naphthalenedicarboxyl)-γ-CD by

• wavelength (296 nm) and the internal filter effect of AC at 350–400 nm is negligible (absorbance <0.1). Considering the nice spectral overlap of the naphthalene fluorescence with the AC absorption (Figure 4), we conclude that Förster resonance energy transfer (FRET) is operating from naphthalene-appended 7